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Supermicro

Validated AMD GPU Systems

Rack-Scale Integration, Testing, and Validation before Shipping

Cluster-scale Deployment, Services, and Support

Storage and Networking Integration

AMD

AMD EPYC™ CPUs

AMD Instinct™ GPUs

AMD Pensando™ Networking

AMD Enterprise Software

Open, Scalable AI Infrastructure for the Future with Supermicro and AMD

Combining Supermicro’s rack-scale integration with AMD datacenter products provides a turnkey infrastructure specifically engineered for the intensive demands of a modern AI factory. By leveraging Supermicro’s liquid-cooling expertise and pre-validated L11 rack solutions, enterprises can deploy various sized clusters of MI350 series accelerators with optimal thermal efficiency and minimal onsite configuration. This collaborative ecosystem significantly accelerates time-to-market, as Supermicro performs pre-validation and qualification of the entire stack before delivery. Ultimately, this partnership reduces the complexity of scaling generative AI workloads, allowing organizations to transition from delivery to full-scale model training in record time.

Supermicro Server Rack with liquid-cooled AMD Instinct GPU servers

AMD Instinct

GPUs set the standard for generative AI and high-performance computing by delivering industry-leading memory capacity and bandwidth—headlined by the MI355X’s 288GB of HBM3E and 8TB/s throughput—enabling seamless execution of the world’s largest language models on fewer nodes.

AMD Open Software Stack

ROCm software stack enable customers an open, end-to-end ecosystem for leading frameworks and libraries and along with the enterprise suite, simplify the AI lifecycle with optimized microservices and solution blueprints.

AMD EPYC

Processors deliver leadership performance by combining industry-high core counts of up to 192 “Zen 5” cores with superior memory bandwidth, providing a highly efficient foundation for end-to-end AI workloads.

AMD Pensando

AI NICs maximize AI cluster efficiency by utilizing a fully programmable P4 pipeline and Ultra Ethernet Consortium (UEC)-ready features—like intelligent packet spraying and path-aware congestion control—to reduce job completion times by up to 20% compared to traditional RoCEv2 solutions.

Storage

Supermicro and AMD work with leading storage vendors to create a full stack solution that can be seamlessly connected to the validated AI Platform solutions.

Supermicro  L11 BOM SKU #SRS-48UAC-MI350-8U4N-R0SRS-48UAC-MI355-10U4N-R0SRS-48ULC-MI355-4U8N-R0SRS-52ULC-MI355-4U12N-R0
Supermicro ServerAS -8126GS-TNMRAS -A126GS-TNMRAS -4126GS-NMR-LCCAS -4126GS-NMR-LCC
Server CoolingAirAirLiquidLiquid
GPU FamilyMI350XMI355XMI355XMI355X
Server Cluster Size (S, M, L)4, 16, 644, 16, 644, 32, 648, 48, 128
Number of Instinct GPUs32, 128, 51232, 128, 51232, 256, 51264, 384, 1024
Instinct GPU ModelMI350X ACMI355X AC MI355X DLCMI355X DLC
Number of Pensando AI NICs40, 160, 64040, 160, 64040, 320, 64080, 480, 1280
Rack Power (for Middle Cluster Size)48.47 kW63.61 kW120.36 kW178.71 kW

Featured Products

10U GPU A+ Server

AS -A126GS-TNMR
DP 10U AMD GPU System with AMD Instinct™ MI355X Accelerators

8U GPU A+ Server

AS -8126GS-TNMR
DP AMD 8U System with AMD Instinct™ MI325X 8-GPU

4U GPU A+ Server

AS -4126GS-NMR-LCC
DP AMD 4U Liquid-Cooled System with AMD Instinct™ MI355X 8-GPU (onsite service is required for liquid-cooling)

4U GPU A+ Server

AS -4125GS-TNMR2-LCC
DP AMD 4U Liquid-Cooled System with AMD Instinct™ MI300X 8-GPU (onsite service is required for liquid-cooling)

2U Hyper A+ Server

AS -2126HS-TN
2U Hyper with up to 24 hot-swap 2.5" NVMe/SAS/SATA bays and 4 PCIe 5.0 x16 slots + 1 PCIe 5.0 x16 AIOM slot

5-Node MicroCloud

AS -3015MR-H5TNR
3U 5-Node MicroCloud with double-width GPU support

4U GPU A+ Server

AS -4145GH-TNMR
4U System with Quad AMD Instinct™ MI300A Accelerators (onsite service OSNBD is required)

5U GPU A+ Server

AS -5126GS-TNRT
DP AMD 5U System with 8 PCIe GPUs

FlexTwin A+ Server

AS-2126FT-HE-LCC
2U 4-Node FlexTwin™ with liquid cooling (complete rack and onsite service are required)
Featured Resources

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